Astatine 211 (At) – Specialist Radioisotope for Targeted Alpha Therapy & Research
We supply ultra-high-purity Astatine-211 (²¹¹At) in trace research quantities for qualified institutions. This rare, highly radioactive halogen isotope emits powerful alpha particles with a short, 7.2-hour half-life. Consequently, the medical research and radiopharmaceutical sector actively investigates it for targeted alpha therapy (TAT) in oncology. Moreover, its unique decay properties make it a promising candidate for treating microscopic cancers with minimal damage to surrounding healthy tissue.
Core Applications for Astatine-211 in Medical Research
This highly specialized radioisotope serves an emerging and critical role in next-generation cancer treatment research. Its application is focused solely on advanced biomedical science.
First, leading cancer research centers and radiopharmaceutical developers utilize Astatine-211 for experimental targeted alpha therapy (TAT). Researchers conjugate it to tumor-targeting molecules (like monoclonal antibodies) to deliver a highly potent, short-range cytotoxic dose directly to cancer cells. Therefore, the global research community values it for its potential to develop precise, powerful treatments for leukemia, glioblastoma, and metastatic cancers.
Second, its use is confined to fundamental nuclear chemistry and physics research due to its scarcity and complex handling requirements.
Critical Specifications for Astatine-211 (²¹¹At)
We produce and supply ²¹¹At via proton bombardment of Bismuth-209, followed by state-of-the-art radiochemical separation. Thus, our product meets the exacting purity and specific activity requirements for sensitive biological research.
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Product: Astatine-211 Radioisotope
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Half-Life: 7.214 hours
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Form: Typically supplied in a specific chemical form (e.g., astatide) in a small volume of solvent, suitable for immediate radiolabeling research.
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Specific Activity: Extremely high (> theoretical).
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Handling: CRITICAL: Requires handling in licensed radiochemical facilities with appropriate infrastructure (hot cells, alpha-particle shielding, trained personnel) and compliance with all national and international nuclear regulatory frameworks (IAEA, etc.).
As a specialized partner to the global nuclear medicine research community, we provide access to this rare and promising isotope.
Firstly, we guarantee high radiochemical purity and minimal isotopic contaminants through our advanced cyclotron production and separation protocols.
Moreover, we provide secure, customized delivery of time-sensitive shipments directly to your licensed facility, coordinated to match your experimental schedule due to the short half-life.
We offer project-based pricing for this highly specialized material, structured to support academic research institutions, hospital cyclotron facilities, and radiopharmaceutical R&D companies.
Additionally, we manage full regulatory compliance and documentation for the international transport of radioactive materials, ensuring a seamless and legal supply chain.
Finally, we provide dedicated scientific liaison support to discuss specific activity, formulation, and integration into your preclinical or clinical research protocols.